Royalty and politicians
- Alfred the Great, 9th-century King of Wessex
- Alfred Aetheling (died 1036), son of King Ethelred II of England
- Alfred, Duke of Saxe-Coburg and Gotha (1844–1900), second son and fourth child of Queen Victoria of the United Kingdom and Prince Albert of Saxe-Coburg and Gotha
- Alfred, Hereditary Prince of Saxe-Coburg and Gotha, grandson of Queen Victoria and son of Alfred, Duke of Saxe-Coburg and Gotha
- Alfred A. Lama (1899–1984), Italian-American architect and politician
- Alfred Bansard des Bois (1848–1920), French politician
- Alfred Winsor Brown, governor of Guam
- Alfred Deakin (1856–1919), 2nd Prime Minister of Australia
- Alfred Joseph Richard de Soysa (1869-1939), Sri Lankan Sinhala landowner and member of the Legislative Council of Ceylon
- Alfred Dregger (1920–2002), German politician
- Alfred Gusenbauer (born 1960), Austrian politician
- Alfred Käärmann (1922–2010), Estonian freedom fighter
- Alf Landon, American politician
- Alfred Lecerf, Belgian politician
- Alfred Mtsi (1950/1951–2020), South African politician
- Al Smith, American statesman
- Alfred Graf von Schlieffen (1833–1913), German field marshal and strategist
